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Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
BACKGROUND: Effective targeting therapies for common chronic liver disease nonalcoholic steatohepatitis (NASH) are in urgent need. MicroRNA-targeted therapeutics would be potentially an effective treatment strategy of hepatic diseases. Here we investigated the functional role of miR-221/222 and the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284352/ https://www.ncbi.nlm.nih.gov/pubmed/30316865 http://dx.doi.org/10.1016/j.ebiom.2018.09.051 |