Cargando…

Development of Severe Combined Immunodeficient (SCID) Pig Models for Translational Cancer Modeling: Future Insights on How Humanized SCID Pigs Can Improve Preclinical Cancer Research

Within the last decade there have been several severe combined immunodeficient (SCID) pig models discovered or genetically engineered. The animals have mutations in ARTEMIS, IL2RG, or RAG1/2 genes, or combinations thereof, providing SCID pigs with NK cells, but deficient in T and B cells, or deficie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boettcher, Adeline N., Loving, Crystal L., Cunnick, Joan E., Tuggle, Christopher K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284365/ https://www.ncbi.nlm.nih.gov/pubmed/30560086 http://dx.doi.org/10.3389/fonc.2018.00559

Ejemplares similares

Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs
por: Boettcher, Adeline N., et al.
Publicado: (2019)

Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART(−/−) IL2RG(−/Y) SCID Pigs
por: Boettcher, Adeline N., et al.
Publicado: (2020)

Production and rearing of germ-free X-SCID pigs
por: Hara, Hiromasa, et al.
Publicado: (2017)

CD3ε(+) Cells in Pigs With Severe Combined Immunodeficiency Due to Defects in ARTEMIS
por: Boettcher, Adeline N., et al.
Publicado: (2020)

The immunodeficient scid mouse as a model for human lymphatic filariasis
Publicado: (1991)

Genetics of SCID
por: Cossu, Fausto
Publicado: (2010)

Universal Newborn Screening for Severe Combined Immunodeficiency (SCID)
por: van der Burg, Mirjam, et al.
Publicado: (2019)

A severe combined immunodeficient (SCID) mouse model for infection with Entamoeba histolytica
Publicado: (1992)

Zebrafish Model of Severe Combined Immunodeficiency (SCID) Due to JAK3 Mutation
por: Basheer, Faiza, et al.
Publicado: (2022)

Thymic epithelial cells of severe combined immunodeficiency (SCID) mice.
por: Lee, I., et al.
Publicado: (1994)

Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)
por: Haddad, Elie, et al.
Publicado: (2019)

Severe Combined Immunodeficiency (SCID) and Its New Treatment Modalities
por: Wadbudhe, Akshad M, et al.
Publicado: (2023)

Preclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID model
por: Brady, Jamie L, et al.
Publicado: (2014)

Severe combined immunodeficiency (SCID) in man: B cell-negative (B-) SCID patients exhibit an irregular recombination pattern at the JH locus
Publicado: (1991)

Rapid Growth and Spontaneous Metastasis of Human Germinal Tumors Ectopically Transplanted into Scid (Severe Combined Immunodeficiency) and Scid‐nude(streaker) Mice
por: Nomura, Taisei, et al.
Publicado: (1991)

Persistent Infection with Rotavirus Vaccine Strain in Severe Combined Immunodeficiency (SCID) Child: Is Rotavirus Vaccination in SCID Children a Janus Face?
por: De Francesco, Maria Antonia, et al.
Publicado: (2019)

Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain(null) Mice
por: Cai, Shanbao, et al.
Publicado: (2011)

The severe combined immunodeficiency (scid) mouse. A laboratory model for the analysis of Lyme arthritis and carditis
Publicado: (1989)

A high-quality severe combined immunodeficiency (SCID) rat bioresource
por: Miyasaka, Yoshiki, et al.
Publicado: (2022)

Implementation of SCID Screening in Denmark
por: Bækvad-Hansen, Marie, et al.
Publicado: (2021)

Transfer of human systemic lupus erythematosus in severe combined immunodeficient (SCID) mice
Publicado: (1990)

Severe Combined Immunodeficiency (SCID) in Canadian Children: A National Surveillance Study
por: Rozmus, Jacob, et al.
Publicado: (2013)

Review of Treatment for Adenosine Deaminase Deficiency (ADA) Severe Combined Immunodeficiency (SCID)
por: Secord, Elizabeth, et al.
Publicado: (2022)

The SCID Mouse Model for Identifying Virulence Determinants in Coxiella burnetii
por: van Schaik, Erin J., et al.
Publicado: (2017)

Treatment of lycorine on SCID mice model with human APL cells
por: Liu, J., et al.
Publicado: (2007)

Reevaluation of NOD/SCID Mice as NK Cell-Deficient Models
por: Miao, Miao, et al.
Publicado: (2021)

A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells
por: Calimeri, T, et al.
Publicado: (2011)

Clinical Spectrum of SCID: The Key is in the Thymus?
por: van der Burg, Mirjam, et al.
Publicado: (2014)

Neonatal Screening for SCID: The French Experience
por: Audrain, Marie, et al.
Publicado: (2021)

Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras
Publicado: (1994)

Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID)
por: Booth, Claire, et al.
Publicado: (2009)

Facial vein injection of human cells in severe combined immunodeficiency (SCID) neonatal mice
por: Pavathuparambil Abdul Manaph, Nimshitha, et al.
Publicado: (2018)

Introducing Newborn Screening for Severe Combined Immunodeficiency (SCID) in the Dutch Neonatal Screening Program
por: Blom, Maartje, et al.
Publicado: (2018)

Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID
por: Garcia-Perez, Laura, et al.
Publicado: (2020)

Differential Post-Surgical Metastasis and Survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγ(null) Mice with Parental and Subline Variants of Human Breast Cancer: Implications for Host Defense Mechanisms Regulating Metastasis
por: Milsom, Chloe C., et al.
Publicado: (2013)

Reference genomes for BALB/c Nude and NOD/SCID mouse models
por: Schmid-Siegert, Emanuel, et al.
Publicado: (2023)

Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse
Publicado: (1993)

Generation of biliary lesions after transfer of human lymphocytes into severe combined immunodeficient (SCID) mice
Publicado: (1989)

Clinical, Immunological, and Molecular Findings in 57 Patients With Severe Combined Immunodeficiency (SCID) From India
por: Aluri, Jahnavi, et al.
Publicado: (2019)

Gene therapy of destructive arthritis in SCID mice
por: Sack, U, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_q06oiejqcjuardmg4p8rvs6ehh