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Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade

Emerging evidence suggests a role for radiation in eliciting anti‐tumour immunity. We aimed to investigate the role of macrophages in modulating the immune response to radiation. Irradiation to murine tumours generated from colorectal (MC38) and pancreatic (KPC) cell lines induced colony‐stimulating...

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Detalles Bibliográficos
Autores principales: Jones, Keaton I, Tiersma, Jiske, Yuzhalin, Arseniy E, Gordon‐Weeks, Alex N, Buzzelli, Jon, Im, Jae Hong, Muschel, Ruth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284388/
https://www.ncbi.nlm.nih.gov/pubmed/30442705
http://dx.doi.org/10.15252/emmm.201809342