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Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression
BACKGROUND: Glioblastoma (GBM) is the most frequent and malignant primary brain tumor in adults and despite the progress in surgical procedures and therapy options, the overall survival remains very poor. Glutamate and α-KG are fundamental elements necessary to support the growth and proliferation o...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284416/ https://www.ncbi.nlm.nih.gov/pubmed/30314897 http://dx.doi.org/10.1016/j.ebiom.2018.10.008 |