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Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression

BACKGROUND: Glioblastoma (GBM) is the most frequent and malignant primary brain tumor in adults and despite the progress in surgical procedures and therapy options, the overall survival remains very poor. Glutamate and α-KG are fundamental elements necessary to support the growth and proliferation o...

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Detalles Bibliográficos
Autores principales: Franceschi, Sara, Corsinovi, Debora, Lessi, Francesca, Tantillo, Elena, Aretini, Paolo, Menicagli, Michele, Scopelliti, Claudia, Civita, Prospero, Pasqualetti, Francesco, Naccarato, Antonio G., Ori, Michela, Mazzanti, Chiara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284416/
https://www.ncbi.nlm.nih.gov/pubmed/30314897
http://dx.doi.org/10.1016/j.ebiom.2018.10.008