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Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure
BACKGROUND: Hepatic encephalopathy (HE), a severe neuropsychiatric complication, is associated with increased blood levels of ammonia and bile acids (BAs). We sought to determine (1) whether abnormally increased blood BAs in liver cirrhotic patients with HE is caused by elevation of apical sodium-de...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284422/ https://www.ncbi.nlm.nih.gov/pubmed/30344125 http://dx.doi.org/10.1016/j.ebiom.2018.10.030 |