Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure

BACKGROUND: Hepatic encephalopathy (HE), a severe neuropsychiatric complication, is associated with increased blood levels of ammonia and bile acids (BAs). We sought to determine (1) whether abnormally increased blood BAs in liver cirrhotic patients with HE is caused by elevation of apical sodium-de...

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Detalles Bibliográficos
Autores principales: Xie, Guoxiang, Wang, Xiaoning, Jiang, Runqiu, Zhao, Aihua, Yan, Jingyu, Zheng, Xiaojiao, Huang, Fengjie, Liu, Xinzhu, Panee, Jun, Rajani, Cynthia, Yao, Chun, Yu, Herbert, Jia, Weiping, Sun, Beicheng, Liu, Ping, Jia, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284422/
https://www.ncbi.nlm.nih.gov/pubmed/30344125
http://dx.doi.org/10.1016/j.ebiom.2018.10.030

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