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Distinctive Roles of Sirtuins on Diabetes, Protective or Detrimental?

Dysregulation of metabolic pathways leads to type 2 diabetes, characteristic of high glucose concentration caused by insulin resistance. The histone deacetylases sirtuins exhibit remarkable enzymatic activities. Accumulating evidence indicates that sirtuins can be pharmacologically activated to amel...

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Detalles Bibliográficos
Autores principales: Song, Jie, Yang, Bing, Jia, Xiaobin, Li, Mingyu, Tan, Wei, Ma, Shitang, Shi, Xinhong, Feng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284472/
https://www.ncbi.nlm.nih.gov/pubmed/30559718
http://dx.doi.org/10.3389/fendo.2018.00724