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Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model

The placenta responds to adverse environmental conditions by adapting its capacity for substrate transfer to maintain fetal growth and development. Early-onset hypoxia effects on placental morphology and activation of the unfolded protein response (UPR) were determined using an established rat model...

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Detalles Bibliográficos
Autores principales: Nuzzo, Anna M., Camm, Emily J., Sferruzzi-Perri, Amanda N., Ashmore, Thomas J., Yung, Hong-wa, Cindrova-Davies, Tereza, Spiroski, Ana-Mishel, Sutherland, Megan R., Logan, Angela, Austin-Williams, Shani, Burton, Graham J., Rolfo, Alessandro, Todros, Tullia, Murphy, Michael P., Giussani, Dino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284551/
https://www.ncbi.nlm.nih.gov/pubmed/30248337
http://dx.doi.org/10.1016/j.ajpath.2018.07.027