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Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging

Antibody pretargeting is a promising strategy for improving molecular imaging, wherein the separation in time of antibody targeting and radiolabeling can lead to rapid attainment of high contrast, potentially increased sensitivity, and reduced patient radiation exposure. The inverse electron demand...

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Detalles Bibliográficos
Autores principales: Mandikian, Danielle, Rafidi, Hanine, Adhikari, Pragya, Venkatraman, Priya, Nazarova, Lidia, Fung, Gabriel, Figueroa, Isabel, Ferl, Gregory Z., Ulufatu, Sheila, Ho, Jason, McCaughey, Cynthia, Lau, Jeffrey, Yu, Shang-Fan, Prabhu, Saileta, Sadowsky, Jack, Boswell, C. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284555/
https://www.ncbi.nlm.nih.gov/pubmed/30199303
http://dx.doi.org/10.1080/19420862.2018.1521132