A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture

Immunoglobulin G–like bispecific antibodies with asymmetric architecture are among the most widely used bispecific antibody formats for diagnostic and therapeutic applications. The primary technical challenge for this format is how to achieve correctly paired assembly of four unique polypeptide chai...

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Detalles Bibliográficos
Autores principales: Wang, Chunlei, Vemulapalli, Bhargavi, Cao, Mingyan, Gadre, Dhanesh, Wang, Jihong, Hunter, Alan, Wang, Xiangyang, Liu, Dengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284573/
https://www.ncbi.nlm.nih.gov/pubmed/30153083
http://dx.doi.org/10.1080/19420862.2018.1511198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284573/
https://www.ncbi.nlm.nih.gov/pubmed/30153083
http://dx.doi.org/10.1080/19420862.2018.1511198

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