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A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture
Immunoglobulin G–like bispecific antibodies with asymmetric architecture are among the most widely used bispecific antibody formats for diagnostic and therapeutic applications. The primary technical challenge for this format is how to achieve correctly paired assembly of four unique polypeptide chai...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284573/ https://www.ncbi.nlm.nih.gov/pubmed/30153083 http://dx.doi.org/10.1080/19420862.2018.1511198 |