Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions

The advantages of site-specific over stochastic bioconjugation technologies include homogeneity of product, minimal perturbation of protein structure/function, and – increasingly – the ability to perform structure activity relationship studies at the conjugate level. When selecting the optimal locat...

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Detalles Bibliográficos
Autores principales: Huang, Betty C. B., Kim, Yun Cheol, Bañas, Stefanie, Barfield, Robyn M., Drake, Penelope M., Rupniewski, Igor, Haskins, William E., Rabuka, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284588/
https://www.ncbi.nlm.nih.gov/pubmed/30252630
http://dx.doi.org/10.1080/19420862.2018.1512327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284588/
https://www.ncbi.nlm.nih.gov/pubmed/30252630
http://dx.doi.org/10.1080/19420862.2018.1512327

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