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Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions
The advantages of site-specific over stochastic bioconjugation technologies include homogeneity of product, minimal perturbation of protein structure/function, and – increasingly – the ability to perform structure activity relationship studies at the conjugate level. When selecting the optimal locat...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284588/ https://www.ncbi.nlm.nih.gov/pubmed/30252630 http://dx.doi.org/10.1080/19420862.2018.1512327 |