Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method

Monoclonal antibodies (mAbs) have become a major class of protein therapeutics that target a spectrum of diseases ranging from cancers to infectious diseases. Similar to any protein molecule, mAbs are susceptible to chemical modifications during the manufacturing process, long-term storage, and in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Sankar, Kannan, Hoi, Kam Hon, Yin, Yizhou, Ramachandran, Prasanna, Andersen, Nisana, Hilderbrand, Amy, McDonald, Paul, Spiess, Christoph, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284603/
https://www.ncbi.nlm.nih.gov/pubmed/30252602
http://dx.doi.org/10.1080/19420862.2018.1518887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284603/
https://www.ncbi.nlm.nih.gov/pubmed/30252602
http://dx.doi.org/10.1080/19420862.2018.1518887

Ejemplares similares