Cargando…
Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method
Monoclonal antibodies (mAbs) have become a major class of protein therapeutics that target a spectrum of diseases ranging from cancers to infectious diseases. Similar to any protein molecule, mAbs are susceptible to chemical modifications during the manufacturing process, long-term storage, and in v...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284603/ https://www.ncbi.nlm.nih.gov/pubmed/30252602 http://dx.doi.org/10.1080/19420862.2018.1518887 |