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The estrogen receptor variants β2 and β5 induce stem cell characteristics and chemotherapy resistance in prostate cancer through activation of hypoxic signaling

Chemotherapy resistant prostate cancer is a major clinical problem. When the prostate cancer has become androgen deprivation resistant, one of the few treatment regimens left is chemotherapy. There is a strong connection between a cancer’s stem cell like characteristics and drug resistance. By perfo...

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Detalles Bibliográficos
Autores principales: Faria, Michelle, Shepherd, Peter, Pan, Yinghong, Chatterjee, Sujash S., Navone, Nora, Gustafsson, Jan-Åke, Strom, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284737/
https://www.ncbi.nlm.nih.gov/pubmed/30555629
http://dx.doi.org/10.18632/oncotarget.26345