Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells

Glyoxalase 1 (GLO1) is a ubiquitous enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis that induces apoptosis. In this study, we found that GLO1 gene expression correlates with neoplasm histologic grade (χ(2) test, p = 0.002) and is elevated in human basal-li...

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Detalles Bibliográficos
Autores principales: Tamori, Shoma, Nozaki, Yuka, Motomura, Hitomi, Nakane, Hiromi, Katayama, Reika, Onaga, Chotaro, Kikuchi, Eriko, Shimada, Nami, Suzuki, Yuhei, Noike, Mei, Hara, Yasushi, Sato, Keiko, Sato, Tsugumichi, Yamamoto, Kouji, Hanawa, Takehisa, Imai, Misa, Abe, Ryo, Yoshimori, Atsushi, Takasawa, Ryoko, Tanuma, Sei-Ichi, Akimoto, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284866/
https://www.ncbi.nlm.nih.gov/pubmed/30559934
http://dx.doi.org/10.18632/oncotarget.26369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284866/
https://www.ncbi.nlm.nih.gov/pubmed/30559934
http://dx.doi.org/10.18632/oncotarget.26369

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