Cargando…

Mbd3 Promotes Reprogramming of Primary Human Fibroblasts

Mbd3 (Methyl-CpG binding domain protein), a core member of NuRD (nucleosome remodelling and deacetylation) is essential for embryogenesis. However, its role in reprogramming of somatic cells into induced pluripotent stem cells (iPSC) remains controversial. Some reports suggest that Mbd3 inhibits plu...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaffer, Sajjida, Goh, Pollyanna, Abbasian, Mahnaz, Nathwani, Amit C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285286/
https://www.ncbi.nlm.nih.gov/pubmed/30497130
http://dx.doi.org/10.15283/ijsc18036