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The Pharmacological Inhibition of ERK5 Enhances Apoptosis in Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is a fatal hematological malignancy which is resistant to a variety of chemotherapy drugs. Extracellular signal-regulated kinase 5 (ERK5) plays a novel role in chemoresistance in some cancer cells and this pathway is a central mediator of cell survival and apoptotic regu...

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Detalles Bibliográficos
Autores principales: Kang, Changhee, Kim, Jong Soo, Kim, C-Yoon, Kim, Eun-Young, Chung, Hyung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285287/
https://www.ncbi.nlm.nih.gov/pubmed/30343550
http://dx.doi.org/10.15283/ijsc18053