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Effect of Stem Cells and Gene Transfected Stem Cells Therapy on the Pancreas of Experimentally Induced Type 1 Diabetes

BACKGROUND AND OBJECTIVES: Insulin secretion entirely depends on Ca(2+) influx and sequestration into endoplasmic reticulum (ER) of β-cells, performed by Sarco-ER Ca(2)(+)-ATPase 2b (SERCA2b). In diabetes, SERCA2b is decreased in the β-cells leading to impaired intracellular Ca(2+) homeostasis and i...

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Detalles Bibliográficos
Autores principales: Zickri, Maha Baligh, Aboul-Fotouh, Gihan Ibrahim, Omar, Abeer Ibraheem, El-Shafei, Asmaa Ahmed, Reda, Ahmed Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285289/
https://www.ncbi.nlm.nih.gov/pubmed/30021252
http://dx.doi.org/10.15283/ijsc18002