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Effect of Stem Cells and Gene Transfected Stem Cells Therapy on the Pancreas of Experimentally Induced Type 1 Diabetes
BACKGROUND AND OBJECTIVES: Insulin secretion entirely depends on Ca(2+) influx and sequestration into endoplasmic reticulum (ER) of β-cells, performed by Sarco-ER Ca(2)(+)-ATPase 2b (SERCA2b). In diabetes, SERCA2b is decreased in the β-cells leading to impaired intracellular Ca(2+) homeostasis and i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Stem Cell Research
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285289/ https://www.ncbi.nlm.nih.gov/pubmed/30021252 http://dx.doi.org/10.15283/ijsc18002 |