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Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors
Cancer metabolism has received renewed interest as a potential target for cancer therapy. In this study, we use a multi-scale modeling approach to interrogate the implications of three metabolic scenarios of potential clinical relevance: the Warburg effect, the reverse Warburg effect and glutamine a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285468/ https://www.ncbi.nlm.nih.gov/pubmed/30532226 http://dx.doi.org/10.1371/journal.pcbi.1006584 |