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Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors

Cancer metabolism has received renewed interest as a potential target for cancer therapy. In this study, we use a multi-scale modeling approach to interrogate the implications of three metabolic scenarios of potential clinical relevance: the Warburg effect, the reverse Warburg effect and glutamine a...

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Detalles Bibliográficos
Autores principales: Shan, Mengrou, Dai, David, Vudem, Arunodai, Varner, Jeffrey D., Stroock, Abraham D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285468/
https://www.ncbi.nlm.nih.gov/pubmed/30532226
http://dx.doi.org/10.1371/journal.pcbi.1006584