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Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines

An emerging method to help elucidate the mode of action of experimental drugs is to use untargeted metabolomics of cell-systems. The interpretations of such screens are however complex and more examples with inhibitors of known targets are needed. Here two T-cell lines were treated with an inhibitor...

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Detalles Bibliográficos
Autores principales: Antti, Henrik, Sellstedt, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285999/
https://www.ncbi.nlm.nih.gov/pubmed/30532126
http://dx.doi.org/10.1371/journal.pone.0208025