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Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages

How Mycobacterium tuberculosis (Mtb) rewires macrophage energy metabolism to facilitate survival is poorly characterized. Here, we used extracellular flux analysis to simultaneously measure the rates of glycolysis and respiration in real time. Mtb infection induced a quiescent energy phenotype in hu...

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Detalles Bibliográficos
Autores principales: Cumming, Bridgette M, Addicott, Kelvin W, Adamson, John H, Steyn, Adrie JC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286123/
https://www.ncbi.nlm.nih.gov/pubmed/30444490
http://dx.doi.org/10.7554/eLife.39169