A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

Intracellular lipopolysaccharide (LPS) triggers the non-canonical inflammasome pathway, resulting in pyroptosis of innate immune cells. In addition to its well-known proinflammatory role, LPS can directly cause regression of some tumors, although the underlying mechanism has remained unknown. Here w...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Shigetoshi, Cai, Yan, Murata, Miyuki, Tomita, Takeshi, Yoneda, Mitsuhiro, Xu, Lei, Pilon, Aprile L, Cachau, Raul E, Kimura, Shioko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286126/
https://www.ncbi.nlm.nih.gov/pubmed/30526845
http://dx.doi.org/10.7554/eLife.37854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286126/
https://www.ncbi.nlm.nih.gov/pubmed/30526845
http://dx.doi.org/10.7554/eLife.37854

Ejemplares similares