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A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

Intracellular lipopolysaccharide (LPS) triggers the non-canonical inflammasome pathway, resulting in pyroptosis of innate immune cells. In addition to its well-known proinflammatory role, LPS can directly cause regression of some tumors, although the underlying mechanism has remained unknown. Here w...

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Detalles Bibliográficos
Autores principales:	Yokoyama, Shigetoshi, Cai, Yan, Murata, Miyuki, Tomita, Takeshi, Yoneda, Mitsuhiro, Xu, Lei, Pilon, Aprile L, Cachau, Raul E, Kimura, Shioko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286126/ https://www.ncbi.nlm.nih.gov/pubmed/30526845 http://dx.doi.org/10.7554/eLife.37854

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