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Prosaposin promotes the proliferation and tumorigenesis of glioma through toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway

BACKGROUND: As a neurotrophic factor, prosaposin (PSAP) can exert neuroprotective and neurotrophic effects. It is involved in the occurrence and development of prostate and breast cancer. However, there is no research about the role of PSAP in glioma. METHODS: The PSAP overexpressed or silenced glio...

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Detalles Bibliográficos
Autores principales: Jiang, Yang, Zhou, Jinpeng, Luo, Peng, Gao, Huiling, Ma, Yanju, Chen, Yin-Sheng, Li, Long, Zou, Dan, Zhang, Ye, Jing, Zhitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286187/
https://www.ncbi.nlm.nih.gov/pubmed/30385233
http://dx.doi.org/10.1016/j.ebiom.2018.10.053