Transmembrane but not soluble helices fold inside the ribosome tunnel

Integral membrane proteins are assembled into the ER membrane via a continuous ribosome-translocon channel. The hydrophobicity and thickness of the core of the membrane bilayer leads to the expectation that transmembrane (TM) segments minimize the cost of harbouring polar polypeptide backbones by ad...

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Detalles Bibliográficos
Autores principales: Bañó-Polo, Manuel, Baeza-Delgado, Carlos, Tamborero, Silvia, Hazel, Anthony, Grau, Brayan, Nilsson, IngMarie, Whitley, Paul, Gumbart, James C., von Heijne, Gunnar, Mingarro, Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286305/
https://www.ncbi.nlm.nih.gov/pubmed/30531789
http://dx.doi.org/10.1038/s41467-018-07554-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286305/
https://www.ncbi.nlm.nih.gov/pubmed/30531789
http://dx.doi.org/10.1038/s41467-018-07554-7

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