Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency

Cationic charge and hydrophobicity have long been understood to drive the potency and selectivity of antimicrobial peptides (AMPs). However, these properties alone struggle to guide broad success in vivo, where AMPs must differentiate bacterial and mammalian cells, while avoiding complex barriers. N...

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Detalles Bibliográficos
Autores principales: Brown, Joseph S., Mohamed, Zeinab J., Artim, Christine M., Thornlow, Dana N., Hassler, Joseph F., Rigoglioso, Vincent P., Daniel, Susan, Alabi, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286309/
https://www.ncbi.nlm.nih.gov/pubmed/30534612
http://dx.doi.org/10.1038/s42003-018-0230-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286309/
https://www.ncbi.nlm.nih.gov/pubmed/30534612
http://dx.doi.org/10.1038/s42003-018-0230-4

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