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Xrp1 is a transcription factor required for cell competition-driven elimination of loser cells

The elimination of unfit cells from a tissue is a process known in Drosophila and mammals as cell competition. In a well-studied paradigm “loser” cells that are heterozygous mutant for a haploinsufficient ribosomal protein gene are eliminated from developing tissues via apoptosis when surrounded by...

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Detalles Bibliográficos
Autores principales: Baillon, Ludovic, Germani, Federico, Rockel, Claudia, Hilchenbach, Jochen, Basler, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286310/
https://www.ncbi.nlm.nih.gov/pubmed/30531963
http://dx.doi.org/10.1038/s41598-018-36277-4