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Xrp1 is a transcription factor required for cell competition-driven elimination of loser cells
The elimination of unfit cells from a tissue is a process known in Drosophila and mammals as cell competition. In a well-studied paradigm “loser” cells that are heterozygous mutant for a haploinsufficient ribosomal protein gene are eliminated from developing tissues via apoptosis when surrounded by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286310/ https://www.ncbi.nlm.nih.gov/pubmed/30531963 http://dx.doi.org/10.1038/s41598-018-36277-4 |