Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

Left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. Pathological LVH engages transcriptional programs including reactivation of canonical fetal genes and those inducing fibrosis. Histone lysine demethylases (KDMs) are emerging regulators of transcrip...

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Detalles Bibliográficos
Autores principales: Zhang, Qing-Jun, Tran, Tram Anh T., Wang, Ming, Ranek, Mark J., Kokkonen-Simon, Kristen M., Gao, Jason, Luo, Xiang, Tan, Wei, Kyrychenko, Viktoriia, Liao, Lan, Xu, Jianming, Hill, Joseph A., Olson, Eric N., Kass, David A., Martinez, Elisabeth D., Liu, Zhi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286331/
https://www.ncbi.nlm.nih.gov/pubmed/30531796
http://dx.doi.org/10.1038/s41467-018-07173-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286331/
https://www.ncbi.nlm.nih.gov/pubmed/30531796
http://dx.doi.org/10.1038/s41467-018-07173-2

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