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Binding of HMGN proteins to cell specific enhancers stabilizes cell identity

The dynamic nature of the chromatin epigenetic landscape plays a key role in the establishment and maintenance of cell identity, yet the factors that affect the dynamics of the epigenome are not fully known. Here we find that the ubiquitous nucleosome binding proteins HMGN1 and HMGN2 preferentially...

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Detalles Bibliográficos
Autores principales: He, Bing, Deng, Tao, Zhu, Iris, Furusawa, Takashi, Zhang, Shaofei, Tang, Wei, Postnikov, Yuri, Ambs, Stefan, Li, Caiyi Cherry, Livak, Ferenc, Landsman, David, Bustin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286339/
https://www.ncbi.nlm.nih.gov/pubmed/30532006
http://dx.doi.org/10.1038/s41467-018-07687-9