Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission

Dynamin-related protein 1 (Drp1) is essential for mitochondrial and peroxisomal fission. Recent studies propose that Drp1 does not sever but rather constricts mitochondrial membranes allowing dynamin 2 (Dnm2) to execute final scission. Here, we report that unlike Drp1, Dnm2 is dispensable for peroxi...

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Detalles Bibliográficos
Autores principales: Kamerkar, Sukrut C., Kraus, Felix, Sharpe, Alice J., Pucadyil, Thomas J., Ryan, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286342/
https://www.ncbi.nlm.nih.gov/pubmed/30531964
http://dx.doi.org/10.1038/s41467-018-07543-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286342/
https://www.ncbi.nlm.nih.gov/pubmed/30531964
http://dx.doi.org/10.1038/s41467-018-07543-w

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