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Chemosynthesis and characterization of site-specific N-terminally PEGylated Alpha-momorcharin as apotential agent
Alpha-momorcharin (α-MC), a type I ribosome-inactivating protein (RIP) isolated from Momordica charantia seeds, has been extensively studied for its antitumor, antiviral and antifungal activities. However, as an exogenous protein, problems associated with short half-life and strong immunogenicity ha...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286350/ https://www.ncbi.nlm.nih.gov/pubmed/30531997 http://dx.doi.org/10.1038/s41598-018-35969-1 |