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Chemosynthesis and characterization of site-specific N-terminally PEGylated Alpha-momorcharin as apotential agent

Alpha-momorcharin (α-MC), a type I ribosome-inactivating protein (RIP) isolated from Momordica charantia seeds, has been extensively studied for its antitumor, antiviral and antifungal activities. However, as an exogenous protein, problems associated with short half-life and strong immunogenicity ha...

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Detalles Bibliográficos
Autores principales:	Sun, Wenkui, Sun, Jinghui, Zhang, Haowen, Meng, Yanfa, Li, Linli, Li, Gangrui, Zhang, Xu, Meng, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286350/ https://www.ncbi.nlm.nih.gov/pubmed/30531997 http://dx.doi.org/10.1038/s41598-018-35969-1

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