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SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice

Meiotic synapsis and recombination ensure correct homologous segregation and genetic diversity. Asynapsed homologs are transcriptionally inactivated by meiotic silencing, which serves a surveillance function and in males drives meiotic sex chromosome inactivation. Silencing depends on the DNA damage...

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Detalles Bibliográficos
Autores principales:	Hirota, Takayuki, Blakeley, Paul, Sangrithi, Mahesh N., Mahadevaiah, Shantha K., Encheva, Vesela, Snijders, Ambrosius P., ElInati, Elias, Ojarikre, Obah A., de Rooij, Dirk G., Niakan, Kathy K., Turner, James M.A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286383/ https://www.ncbi.nlm.nih.gov/pubmed/30393076 http://dx.doi.org/10.1016/j.devcel.2018.10.004

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