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Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice

BACKGROUND: As the implantation and long-term existence of tumor-specific T cells in host are the prerequisite for adoptive immunotherapy, memory stem T cells (T(SCM)) with self-renewal and differentiation capacity show the greatest potential to implant and long-term exhibit function in vivo, compar...

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Detalles Bibliográficos
Autores principales: Guan, Liping, Li, Xiaoyi, Wei, Jiali, Liang, Zhihui, Yang, Jing, Weng, Xiufang, Wu, Xiongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286512/
https://www.ncbi.nlm.nih.gov/pubmed/30526661
http://dx.doi.org/10.1186/s13287-018-1080-1