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Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice
BACKGROUND: As the implantation and long-term existence of tumor-specific T cells in host are the prerequisite for adoptive immunotherapy, memory stem T cells (T(SCM)) with self-renewal and differentiation capacity show the greatest potential to implant and long-term exhibit function in vivo, compar...
Autores principales: | Guan, Liping, Li, Xiaoyi, Wei, Jiali, Liang, Zhihui, Yang, Jing, Weng, Xiufang, Wu, Xiongwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286512/ https://www.ncbi.nlm.nih.gov/pubmed/30526661 http://dx.doi.org/10.1186/s13287-018-1080-1 |
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