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Role of protein interactions in stabilizing canonical DNA features in simulations of DNA in crowded environments

BACKGROUND: Cellular environments are highly crowded with biological macromolecules resulting in frequent non-specific interactions. While the effect of such crowding on protein structure and dynamics has been studied extensively, very little is known how cellular crowding affects the conformational...

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Detalles Bibliográficos
Autores principales: Yildirim, Asli, Brenner, Nathalie, Sutherland, Robert, Feig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286541/
https://www.ncbi.nlm.nih.gov/pubmed/30555686
http://dx.doi.org/10.1186/s13628-018-0048-y