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A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment

Immunotherapy has ushered in a new era of cancer therapy, and this is also applicable to therapy of hepatocellular carcinoma (HCC). In this context, effective development of therapeutic strategies requires an HCC mouse model with known tumor-associated antigens (TAAs) and an HCC growth reporter. We...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Tzu, Tseng, Tai-Chung, Soong, Ruey-Shyang, Peng, Chun-Yi, Cheng, Yu-Hsing, Huang, Shiu-Feng, Chuang, Tsung-Hsien, Kao, Jia-Horng, Huang, Li-Rung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286542/
https://www.ncbi.nlm.nih.gov/pubmed/30526672
http://dx.doi.org/10.1186/s40425-018-0462-3