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Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

BACKGROUND: Brain tumor vasculature can be significantly compromised and leakier than that of normal brain blood vessels. Little is known if there are vascular permeability alterations in the brain adjacent to tumor (BAT). Changes in BAT permeability may also lead to increased drug permeation in the...

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Detalles Bibliográficos
Autores principales: Mohammad, Afroz S., Adkins, Chris E., Shah, Neal, Aljammal, Rawaa, Griffith, Jessica I. G., Tallman, Rachel M., Jarrell, Katherine L., Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286543/
https://www.ncbi.nlm.nih.gov/pubmed/30526520
http://dx.doi.org/10.1186/s12885-018-5115-x