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Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer
BACKGROUND: Brain tumor vasculature can be significantly compromised and leakier than that of normal brain blood vessels. Little is known if there are vascular permeability alterations in the brain adjacent to tumor (BAT). Changes in BAT permeability may also lead to increased drug permeation in the...
Autores principales: | Mohammad, Afroz S., Adkins, Chris E., Shah, Neal, Aljammal, Rawaa, Griffith, Jessica I. G., Tallman, Rachel M., Jarrell, Katherine L., Lockman, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286543/ https://www.ncbi.nlm.nih.gov/pubmed/30526520 http://dx.doi.org/10.1186/s12885-018-5115-x |
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