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MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1

BACKGROUND: Despite considerable progress in the development of methods for hematopoietic differentiation, efficient generation of transplantable hematopoietic stem cells (HSCs) and other genuine functional blood cells from human embryonic stem cells (hESCs) is still unsuccessful. Therefore, a bette...

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Detalles Bibliográficos
Autores principales: Wang, Mengge, Wang, Hongtao, Wen, Yuqi, Chen, Xiaoyuan, Liu, Xin, Gao, Jie, Su, Pei, Xu, Yuanfu, Zhou, Wen, Shi, Lihong, Zhou, Jiaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286587/
https://www.ncbi.nlm.nih.gov/pubmed/30526668
http://dx.doi.org/10.1186/s13287-018-1074-z