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EZH2 as a therapeutic target for multiple myeloma and other haematological malignancies
Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that is of great interest in human cancer. It has been shown to have a dual nature, as it can act as a gene repressor or activator. Studies have highlighted the various roles of EZH2 in the pathophysiology of multiple myeloma (MM). It...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286605/ https://www.ncbi.nlm.nih.gov/pubmed/30555699 http://dx.doi.org/10.1186/s40364-018-0148-5 |