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Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease
BACKGROUND: Acute kidney injury (AKI) may lead to the development of chronic kidney disease (CKD), i.e. AKI-CKD transition, but the underlying mechanism remains largely unclear. Endoplasmic reticulum (ER) stress is characterized by the accumulation of unfolded or misfolded proteins in ER resulting i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286638/ https://www.ncbi.nlm.nih.gov/pubmed/30314894 http://dx.doi.org/10.1016/j.ebiom.2018.10.006 |