Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease

BACKGROUND: Acute kidney injury (AKI) may lead to the development of chronic kidney disease (CKD), i.e. AKI-CKD transition, but the underlying mechanism remains largely unclear. Endoplasmic reticulum (ER) stress is characterized by the accumulation of unfolded or misfolded proteins in ER resulting i...

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Detalles Bibliográficos
Autores principales: Shu, Shaoqun, Zhu, Jiefu, Liu, Zhiwen, Tang, Chengyuan, Cai, Juan, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286638/
https://www.ncbi.nlm.nih.gov/pubmed/30314894
http://dx.doi.org/10.1016/j.ebiom.2018.10.006

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