NQO1 Is Regulated by PTEN in Glioblastoma, Mediating Cell Proliferation and Oxidative Stress

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with a dismal prognosis, and the patients carrying EGFR-driven tumors with PTEN mutation do not respond to anti-EGFR therapy. The molecular mechanisms for this resistance remain unknown. Here, we show that PTEN induces the expression o...

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Detalles Bibliográficos
Autores principales: Luo, Shilin, Lei, Kecheng, Xiang, Daxiong, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286748/
https://www.ncbi.nlm.nih.gov/pubmed/30595797
http://dx.doi.org/10.1155/2018/9146528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286748/
https://www.ncbi.nlm.nih.gov/pubmed/30595797
http://dx.doi.org/10.1155/2018/9146528

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