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STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update

STING is a newly identified intracellular sensor of foreign and endogenous DNA. STING has been recognized as an activator of immune responses by TBK1/IRF3 and NF-κB pathways, and it is suggested to play critical roles in host defense, autoimmune diseases, and tumor immunity. Recent studies have reve...

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Detalles Bibliográficos
Autores principales: Liu, Song, Guan, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286756/
https://www.ncbi.nlm.nih.gov/pubmed/30595664
http://dx.doi.org/10.1155/2018/1202797