Cell and tissue type independent age-associated DNA methylation changes are not rare but common

Age-associated DNA methylation changes have been widely reported across many different tissue and cell types. Epigenetic ‘clocks’ that can predict chronological age with a surprisingly high degree of accuracy appear to do so independently of tissue and cell-type, suggesting that a component of epige...

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Detalles Bibliográficos
Autores principales: Zhu, Tianyu, Zheng, Shijie C, Paul, Dirk S., Horvath, Steve, Teschendorff, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286821/
https://www.ncbi.nlm.nih.gov/pubmed/30482885
http://dx.doi.org/10.18632/aging.101666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286821/
https://www.ncbi.nlm.nih.gov/pubmed/30482885
http://dx.doi.org/10.18632/aging.101666

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